Organ damage from coronavirus: COVID-19 not only in the lungs
New pandemic organ damage from coronavirus causes a number of diseases that affect more than just the respiratory tract. These include thrombotic complications related to pathological and dangerous blood clotting, cardiac arrhythmias and arrhythmias, acute coronary syndrome, kidney failure, gastrointestinal symptoms, hepatocellular insufficiency, hyperglycemia and ketosis, neurological disorders, coronary disorders. According to researchers, the rate of patients in need of dialysis is very high at 5 to 10%. Doctors also observe neurological disorders in a third of the patients.
Possible organ damage from coronavirus
The virus penetrates and damages many tissues outside the lungs through the ACE2 receptor on human cells. This leads to a number of other lesions, which accordingly lead to the extrapulmonary manifestation of COVID-19. The researchers consider increased blood clotting and the appearance of blood clots as a result of the effect of the coronavirus on the endothelial cells of blood vessels. In addition, the picture of the disease is complicated by an impaired regulation of immune responses. According to researchers, the mechanism of heart damage is still unclear, although they assume that systemic inflammation also plays a role. In his review, the team examined the pathophysiology of the organs observed in Covid-19 with the idea of helping clinicians and scientists identify and monitor the full range of manifestations of SARS-CoV-2 infection. This allows everyone to develop the priorities in research and therapy strategies together.
To combat the complications of heavy COVID-19, scientists recommend using anticoagulants. These are steroids used to suppress immune reactions and inflammatory processes. The main factors that increase the risk of fatal outcome from coronavirus infection have previously been identified by Oxford University. These include obesity, diabetes, severe asthma and other respiratory diseases, chronic pathological diseases of the heart, liver and neurological and autoimmune diseases. The reason for the fatal outcome is the complications against the background of a coronavirus infection. One of the most recent recommendations from scientists to the population is to monitor blood sugar levels and the condition of the cardiovascular system. In addition, the researchers found a link between blood sugar levels and mortality from Covid-19. This is true even if no diabetes has occurred in the past.
Other risk factors
A risk factor is also hyperglycemia, for example, which Chinese scientists have also published a study on. However, age remains one of the main risk factors for fatal outcome and organ damage from coronavirus. According to a publication in Nature magazine, the risk for people over 80 is 20 times higher than for people in the age group 50-59. Men, the elderly and people living alone seem to die more often too. People of African and Asian origin are also at higher risk. These results belong to British researchers who analyzed data from more than 17 million adults and 10,926 deaths. This corresponds to around 40% of all patients.
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